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Medical Research - Infertility

Measuring the effectiveness of Chinese Herbal Medicine in Improving Female Fertility

Trevor A. Wing & Elke S. Sedlmeier.
Journal of Chinese Medicine, number 80, Feb 2006.

Aim: To determine the relationship between female fertility indicators and the administration of Chinese Herbal Medicine (CHM).

Design: A prospective cohort clinical study to measure accepted bio-medical factors that affect female fertility and to determine if CHM can improve these factors as well as pregnancy outcomes.

Setting:A private practice specialising in treating infertility with Traditional Chinese Medicine (TCM). The study took place between November 2003 and December 2004.

Patients: Fifty women with the Western medical diagnosis of unexplained infertility. Interventions: One monitored menstrual cycle measuring pre-treatment fertility factors, followed by treatment with CHM and subsequent measurement of the changes in the same fertility factors.

Results: Significant differences were observed between the two time points for the majority of factors measured. Pregnancies in the same group recorded 6 months after commencement of the last treatment were 28, with 11 live births and 7 miscarriages. Conclusion: The study outcome demonstrates that using Chinese Herbal Medicine results in higher success rates of pregnancy, with no patient side-effects and a reduction in the category of patients conventionally classified as having unexplained infertility.

Effects of electro-acupuncture on corticotropin-releasing factor in rats with experimentally-induced polycystic ovaries

Stener-Victorin E, Lundeberg T, Waldenstrom U, Bileviciute-Ljungar I, Janson PO.
Department of Obstetrics and Gynecology, Goteborg University, Sweden.
Copyright 2001 Harcourt Publishers Ltd.

The aims of the present study were to investigate corticotropin-releasing factor (CRF) concentrations in the brain, the adrenal glands, and the ovaries in rats with estradiol valerate (EV) induced polycystic ovaries (PCO). The effect of 12 electro-acupuncture (EA) treatments on CRF concentrations was also investigated. The CRF concentrations in the median eminence (ME) were significantly increased in rats with PCO (both the PCO control group and the PCO group receiving EA) compared with the healthy control group (veichle control group), indicating increased activity in the hypothalamus-pituitary axis. The CRF concentrations in the ovaries were significantly reduced in the PCO group receiving EA compared with the PCO control group. Also, there was a decrease in comparison withthe healthy control group but the decrease was not as significant. This finding indicates that repeated EA treatments change the neuroendocrinological state in the ovaries, which may play an important role in reproductive failure.